Denver Broncos vs San Francisco 49ers odds and betting data

This is the NFL event page for Denver Broncos vs San Francisco 49ers. You can see and compare odds across different sportsbooks. The matchup is scheduled for Sunday, October 4 at 8:25 PM UTC, and the odds tables below organize every available price by sportsbook, market, team, and outcome so you can quickly scan the best number before placing a bet.

Linewhale highlights the strongest current prices across 52 sportsbooks, including moneyline prices when available, spread points and prices, and over/under totals. Use this page to compare sportsbook odds, identify the best price for each side, review market differences, and open free line movement history for individual odds.

Free line movement for Denver Broncos vs San Francisco 49ers

To see line movement for this event, use the odds table below and click a specific moneyline, spread, or total price. Linewhale will open a free line movement chart for the selected sportsbook and outcome for Denver Broncos vs San Francisco 49ers, can review how that number has changed before you bet.

NFLSunday, Oct 4, 8:25 PM UTC

DBR

Denver

Broncos

Win Probability

43%57%

San Francisco

49ers

SF4

Win Probability

43%57%

Moneyline · Best Across Books

PRO Broncos +134

BET 49ers -132

Spread · Best Across Books

BET Broncos+2.5 +107

POL 49ers-2.5 -104

Total · Best Across Books

VIR Over+47.5 -111

888 Under+47.5 +100

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Moneyline· Pick the winner

Denver Broncos

+134

+133

+132

×4

Fair +130

+128

+127

×2

+126

+125

×9

+124

+122

+121

+120

×10

+118

×2

+116

×2

+115

×5

+114

+112

+110

×2

-110

San Francisco 49ers

Fair -130

-132

×3

-133

×3

-135

×7

-137

-139

-141

×3

-143

×6

-145

×7

-147

×4

-149

×4

-152

×2

-154

×3

-156

-179

Spread· Denver Broncos +2.5 / San Francisco 49ers -2.5

Denver Broncos

+107

Fair +106

+104

+103

+102

×2

+101

+100

×6

-102

×5

-104

-105

×3

-106

-108

×5

-135

San Francisco 49ers

-104

Fair -106

-108

×2

-109

×3

-114

×5

-115

×2

-116

-118

×3

-119

-120

×8

-125

-143

Spread· Denver Broncos +2 / San Francisco 49ers -2

Denver Broncos

Fair +110

+110

+102

+100

San Francisco 49ers

Fair -110

-114

-120

×2

Spread· Denver Broncos +3 / San Francisco 49ers -3

Denver Broncos

Fair -109

-120

×2

San Francisco 49ers

Fair +109

+100

×2

Spread· Denver Broncos -8.5 / San Francisco 49ers +8.5

Denver Broncos

Fair +410

+380

×2

San Francisco 49ers

Fair -410

-588

×2

Total· O/U 47.5

Over

Fair -103

-111

×2

-112

×3

-114

×4

-115

×3

-125

-141

Under

Fair +103

+100

-105

×3

-108

-109

×6

-112

-114

-139

Total· O/U 48

Over

+101

Fair +100

-106

-108

×3

-109

×2

-110

×7

Under

Fair -100

-101

-103

-108

-109

-110

×10

Total· O/U 48.5

Over

+108

Fair +106

+104

×2

+100

-111

Under

Fair -106

-109

×2

-111

-114

-115

Total· O/U 58

Over

Fair +344

+320

×2

Under

Fair -344

-455

×2

Total· O/U 50

Over

+128

Not enough books for a fair line.

Under

-133

Not enough books for a fair line.

Denver Broncos vs San Francisco 49ers betting odds overview

Compare NFL odds for Denver Broncos vs San Francisco 49ers, scheduled for Sunday, October 4 at 8:25 PM UTC. Linewhale tracks moneyline, spread, and total prices across 100+ sportsbooks in 8 regions so you can compare the best available number before placing a bet.

Best moneyline odds

Denver Broncos is listed at +134 on ProphetX, while San Francisco 49ers is listed at -132 on BetOpenly.

Best spread odds

The best listed spread prices are Denver Broncos +2.5 at +107 on BetOpenly and San Francisco 49ers -2.5 at -104 on Polymarket.

Best total odds

The best over price is -111 on Virgin Bet; the best under price is +100 on 888sport. The listed total is 47.5.

Odds can move quickly as sportsbooks adjust to injuries, lineup news, betting volume, and market-making books. Always confirm the final price at the sportsbook before submitting a wager.