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Arizona Cardinals at Seattle Seahawks: Odds and Betting Preview

The Seahawks open as 10.5-to-11.5-point home favorites over the Cardinals on Nov. 8. Here's a full breakdown of the spread, moneyline, and total with the best lines across books.

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Seattle Opens as a Heavy Home Favorite

The Seattle Seahawks host the Arizona Cardinals on Sunday, November 8, with a 1:25 PM PST kickoff at Lumen Field. The odds market tells a clear story: Seattle is a substantial favorite, with the spread sitting between 10.5 and 11.5 points across major sportsbooks and moneyline prices implying roughly an 85-90% win probability for the home side.

A consensus spread of around -11 makes Seattle one of the bigger favorites you will see in a division game this season. That number is notable because divisional matchups typically keep spreads tighter, given familiarity and rivalry motivation. The market is not respecting that narrative here.

Breaking Down the Cardinals vs. Seahawks Moneyline

Seattle's moneyline ranges from -667 at DraftKings and Kalshi to -909 at BetRivers and several Unibet properties. Arizona sits between +440 at Smarkets and LeoVegas on the low end and +600 at BetRivers and Unibet properties on the high end. That is a wide range worth paying attention to.

At -769 (available at Betfred, Caesars, and Unibet UK), Seattle's implied win probability is roughly 88.5%. Run the full range through the Odds Converter and you will find Seattle clustered between 87% and 90% depending on the book, with Arizona at around 10-13% implied probability.

For Cardinals backers willing to take a shot, the variation is meaningful: DraftKings posts Arizona at +470, FanDuel at +560, and Kalshi at +567. Shopping the moneyline is worth the effort given how wide that spread is.

Spread Shopping: Half-Points Matter Here

The spread market offers the clearest shopping opportunities. Here is the current breakdown:

  • +11.5 / -11.5: 1xBet, BetRivers, FanDuel, LeoVegas, Unibet (Netherlands), Unibet (Sweden)
  • +11 / -11: BetOnline.ag, BetUS, Caesars Sportsbook, GTbets, LowVig.ag
  • +10.5 / -10.5: DraftKings

DraftKings is the outlier at -10.5, a full point better for Arizona bettors and a full point worse for Seattle backers compared to most of the market. If you are leaning toward the Cardinals and the points, that DraftKings number is the most valuable line available. Conversely, if you want Seattle to cover, the -11 options are a softer ask, and LowVig.ag posts both sides at -105, making it among the best prices on that number.

The Total: 44.5 Is the Number

The over/under is tightly consolidated at 44.5 across virtually every sportsbook. There is no line shopping to be done on the number itself, but juice varies. For the over, LowVig.ag leads at -108, with GTbets (-109) and BetOnline.ag (-110) close behind. For the under, LowVig.ag again leads at -108, followed by GTbets and LiveScore Bet at -109.

A 44.5-point total alongside an 11-point spread implies a final score somewhere around 27-17. That is not a blowout total, but it does not suggest an offensive showcase either.

What to Watch Before Kickoff

With 12 days until kickoff, a few factors could shift this line before November 8.

Injury reports: A spread this large is vulnerable to injury news. Any significant update on Seattle's offensive line or Arizona's pass rush situation could move this number quickly. Monitor the week-of reports closely.

Line movement: The current range from -10.5 to -11.5 suggests the market has not fully settled. If sharp money pushes the consensus toward -11.5, or if books begin moving off -11, that is a signal worth tracking. Use Line Whale's Line History tool to follow how this spread moves across books in the coming days.

Arizona's ability to cover: The Cardinals have kept games competitive at times this season. Covering a double-digit spread on the road in a division game is a legitimate ask for Seattle, even as a heavy favorite.

Check back closer to Sunday for updated odds at Line Whale's NFL odds page.

Frequently asked questions

Who is favored in the Cardinals vs Seahawks game on November 8?▾

The Seattle Seahawks are heavy favorites at home against the Arizona Cardinals. At the time of writing, the spread ranged from -10.5 to -11.5 depending on the sportsbook, making Seattle one of the larger favorites seen in a division game this season.

What is the point spread for Cardinals at Seahawks Week 10 2025?▾

At the time of writing, the spread ranged from Seattle -10.5 at DraftKings to -11.5 at several books including FanDuel and BetRivers, with -11 available at Caesars and others. The half-point differences are meaningful for bettors on either side.

What is the over/under for the Cardinals vs Seahawks November 8 game?▾

At the time of writing, the over/under was tightly set at 44.5 across virtually every major sportsbook, leaving little opportunity to shop the number itself. Juice varied by book, with LowVig.ag offering -108 on both sides.

What are the Cardinals moneyline odds vs the Seahawks?▾

At the time of writing, Arizona's moneyline ranged from +440 at the low end to +600 at the high end across major sportsbooks. That wide range makes shopping worthwhile for bettors considering the Cardinals.

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